Coffee, also rich in polyphenolic compounds like chlorogenic acid (CGA), caffeic acid (CAA), cafestol, melanoidins and trigonelline, has been recognised as a dominant source of CGA in a number of studies.
Past studies suggest CGA in coffee can positively impact blood pressure, lipid profile, glycemia and insulin resistance, contributing to the improvement of metabolic syndrome and enhancing metabolism, inflammation, cardiovascular health and liver function.
In a new study, researchers examined the effectiveness of coffee against Covid.
They observed data from the UK Biobank to find coffee can be a new strategy to reduce Covid infection by blocking spike protein ACE2 interaction, slowing down TMPRSS2 and CTSL activity and ridding the protein level of TMPRSS2 and ACE2.
Using the HRMS-exploring-recombination-examining method, researchers discovered that isochlorogenic acid A, B, and C in coffee restrict Covid infection (43–54 percent efficiency), as well as decaffeinated coffee.
In the trial, involving 64 people, consuming one to two cups of coffee per day proved effective in stopping entry for multiple Covid variants.
The authors of the study also found consuming coffee within six hours is crucial, with a recommendation to have another cup after this period for better chances to stop the infection
Overall, the authors suggest that coffee intake could be a potential dietary strategy to prevent infection in the post-Covid era.
But drink coffee in moderation – the NHS advises drinking more than four cups of coffee a day may increase your blood pressure.