New therapeutic avenues in bone repair

New therapeutic avenues in bone repair

Birmingham researchers have shown PEPITEM, a naturally occurring peptide (small protein) holds promise as a new therapeutic for osteoporosis and other disorders that feature bone loss, with distinct advantages over existing drugs. PEPITEM (Peptide Inhibitor of Trans-Endothelial Migration) was first identified in 2015 by University of Birmingham researchers. The latest research, published today in Cell … Read more

YAP and TAZ: Protein partners identified as potential key for fetal bone development

New therapeutic avenues in bone repair

A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as “brittle bone disease.” This small animal-based research, published today in Developmental Cell and led by members of the McKay Orthopaedic Research Laboratory of … Read more